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 PROCESSES IN THE NEPHRON 

How the Processes works

1. Renal Corpuscle:

1. BOWMAN'S CAPSULE/PRESSURE FILTRATION:

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  • Is a double-walled cup that lies in the CORTEX region of the kidney

  • It functions to catch and collect filtrate from the glomerulus capillaries

  • It encloses a capillary network called the glomerulus 

  • THE GLOMERULUS AND BOWMAN'S CAPSULE MAKE THE RENAL CORPUSCLE (**this will be on the test**)

  • The outer layer of the capsule is separates from the inner layer by a CAPSULAR SPACE

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  • The passage of water and solutes at the glomerulus and the formation of the glomerular filtrate depends on the pressure at the afferent arteriole.

    • If the pressure rises then filtration rate rises, if the pressure decreases the filtration rate does as well.​

      • This pressure is so well regulated by the body that the filtration rate per day stays almost constant!​

  • After the formation of filtrate, selective reabsorption and secretion modify the urine depending on our bodies needs.

  • Blood pressure forces small particles and water to be squeezed into the Bowman's capsule from the glomerulus capillaries.

FILTRATE COMPOSITION: (small molecules that diffuse into the Bowman's capsule during pressure filtration)

  • Water, Glucose/Amino Acids/ Hydrogen Ions, Salts like NaCl, Urea, Bicarbonate Ions (HCO3), some toxins

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EFFERENT ARTERIOLE COMPOSITION: (large molecules that stay in the blood after pressure filtration)

  • Red Blood Cells, White Blood Cells, Plasma Proteins, Platelets

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